Description
TANIZ is used to treat certain infections caused by bacteria including pneumonia and other lower respiratory lung infections, meningitis (infections of the membranes that surround the brain and spinal cord), skin, bone, joint and urinary tract infections.
Cefuroxime axetil is an orally active prodrug of cefuroxime. After oral administration, cefuroxime axetil, is absorbed from the gastrointestinal tract and rapidly hydrolysed by nonspecific esterases in the intestinal mucosa and blood to release cefuroxime into the blood stream. Conversion to cefuroxime, the microbiologically active form, occurs rapidly. The inherent properties of cefuroxime are unaltered after its administration as cefuroxime acetyl. Cefuroxime exerts its bactericidal effect by binding to an enzyme or enzymes referred to as penicillin-binding proteins (PBPs) involved in bacterial cell wall synthesis.
Taniz Tab
TANIZ Tablets are indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the conditions listed below:
Pharyngitis/Tonsillitis caused by Streptococcus pyogenes. NOTE: The usual drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever, is penicillin given by the intramuscular route.
TANIZ Tablets are generally effective in the eradication of streptococci from the nasopharynx; however, substantial data establishing the efficacy of cefuroxime in the subsequent prevention of rheumatic fever are not available
Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta-lactamase–producing strains), Moraxella catarrhalis (including beta-lactamase–producing strains), or Streptococcus pyogenes.
Acute Bacterial Maxillary Sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non-beta-lactamase–producing strains only).
Acute Bacterial Exacerbations of Chronic Bronchitis and Secondary Bacterial Infections of Acute Bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains), or Haemophilus parainfluenza (beta-lactamase negative strains)
Uncomplicated Skin and Skin-Structure Infections caused by Staphylococcus aureus.
Uncomplicated Urinary Tract Infections caused by Escherichia coli or Klebsiella pneumoniae
Uncomplicated Gonorrhoea, urethral and endocervical, caused by penicillinase-producing and non-penicillinase–producing strains of Neisseria gonorrhoeae and uncomplicated gonorrhoea, rectal, in females, caused by non-penicillinase–producing strains of Neisseria gonorrhoeae.
INDICATIONS
UTI
LRTI
SSTI
