Description
Cefoperazone is a third-generation cephalosporin antibiotic. It is one of few cephalosporin antibiotics effective in treating Pseudomonas bacterial infections which are otherwise resistant to these antibiotics. Cefoperazone has a broad spectrum of activity and has been used to target bacteria responsible for causing infections of the respiratory and urinary tract, skin, and the female genital tract. Cefoperazone exerts its bactericidal effect by inhibiting the bacterial cell wall synthesis
Sulbactam is a β-lactamase inhibitor. This drug is given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys the antibiotics. Sulbactam is an irreversible inhibitor of β-lactamase; it binds to the enzyme and does not allow it to degrade the antibiotic.
This is used in the treatment of infections of skin and skin structures, respiratory tract, urinary tract, gynaecological infections including gonorrhoea, intraabdominal infections, and septicaemia caused by susceptible microorganisms.
INDICATIONS
♦ Upper and Lower Respiratory tract infections.
♦ Upper and lower urinary tract infections.
♦ Peritonitis, Cholecystitis, other intra-abdominal infections.
♦ Cholangitis.
♦ Urinary Tract Infections.
♦ Septicemia , Meningitis .
♦ Skin and soft tissue infections.
♦ Bone and joint infections.
♦ Pelvic inflammatary disease,endometritis, gonorrhea,and other infections of the genital tract.
This should be administered strictly with the prescription and advise of medical practitioners only.